Unveiling Kambo: Ancient Frog Medicine, Modern Healing – An In-Depth Conversation with Caitlin Thompson

What Is Kambo, and How Is It Used?

Caitlin explains that Kambo is a traditional Amazonian ritual utilizing the skin secretion of the Phyllomedusa bicolor frog. Historically, indigenous tribes applied this secretion through small burns on the skin, often to enhance hunting abilities—improving endurance, clarity, and, some say, even luck.

“But now that Kambo has left the jungle and is a lot more widespread in westernized areas, it's evolved into something very different,” Caitlin observes. Whereas it once served hunters, it now attracts seekers pursuing clarity, healing, and personal growth.

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Is Kambo a Psychedelic?

A common misconception is that Kambo is another psychedelic. Caitlin sets the record straight: “Technically speaking, Kambo is not a psychedelic substance. It doesn't have molecules that we would typically classify as psychedelic or hallucinogenic.” Instead, it’s a complex cocktail of bioactive peptides that work with the body’s immune, gastrointestinal, vascular, and neurological systems. Its effects are intense—sweating, nausea, rapid heartbeat—but its true magic often lies in the aftereffects: clarity, heightened perception, and, for some, a sense of spiritual alignment.

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The Risks and Realities

Scott and Caitlin don’t shy away from discussing the less glamorous side of Kambo. The process isn’t pleasant or recreational: “It’s not fun,” Caitlin laughs. “Even people who love it are like, ‘oh shit, here we go again.’” The experience lasts about 20-30 minutes but is physically demanding—a deliberate ordeal.

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While Kambo itself is generally safe, Caitlin emphasizes the importance of practitioner experience and safety protocols. Most adverse incidents stem not from the frog medicine, but from improper water consumption (leading to dangerous electrolyte imbalances) or a lack of basic precautions during sessions. “If we don’t get our act together as a Kambo community… we are going to lose our legal access to Kambo,” she warns, highlighting calls for higher standards, transparency, and self-regulation.

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The Breadth of Kambo’s Modern Applications

Today, people turn to Kambo for a wide range of reasons—from chronic pain, autoimmune conditions, and infections, to depression, anxiety, trauma release, and addiction. Caitlin shares her personal story of healing from lifelong autoimmune issues, describing Kambo as “a path back to yourself,” though she cautions that success depends on a person’s readiness, intention, and follow-up integration work.

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“It doesn’t just do everything for you — it’s not a magic cure. It’s very much like a teacher,” she explains, urging seekers to actively participate in their own healing process.

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Protecting the Future: Sustainability and Synthesis

One concern Caitlin raises is the sustainability of Kambo sourcing as interest grows. Overharvesting could threaten frog populations and indigenous rights. She predicts that part of the medicine’s future may lie in “synthetic, Kambo-inspired cocktails,” allowing more people access to healing benefits while protecting natural ecosystems. “Every molecule is sacred,” Caitlin notes, seeing both natural and synthetic options as allies in the quest for wellness.

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Practical Advice for Exploring Kambo

For those curious about Kambo, Caitlin offers grounded, heartfelt advice:

• Preparation matters: Know your intentions. Clarity brings better outcomes.
• Vet your practitioner: Ask about medical screening and safety protocols. If someone doesn’t ask about your health history, that’s a red flag.
• Discernment is key: Don’t rush the process or let your ego dictate choices. The right setting and support can “make or break your experience.”
• Integration is everything: The work doesn’t end after the ceremony. Real transformation unfolds with continued reflection and action.
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Final Thoughts

The world of sacred medicines is nuanced, and Kambo is no exception. As Caitlin Thompson so eloquently summarizes, we’re called to approach these substances with reverence, critical thinking, and a willingness to do the inner work. “Your practitioner is going to make or break your experience," she reminds us. “Please choose wisely… and follow your heart—your real heart, not your head.”

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For those wanting to dive deeper, Caitlin offers resources, education, and community at medicinefrogkambo.com and kambospecialist.com.

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Curious about other sacred medicines or want to keep up with the latest in psychedelic science and culture? Subscribe to Webdelics and explore the expanding world of conscious healing.

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Written with insight from Caitlin Thompson’s interview on the Webdelics podcast. For the full episode and more information, visit webdelics.com.

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